Is there any huge drawback to running it without an intercooler? I would eventually put a water/meth kit on it but I think running true twins would require a lot of complicated intercooler piping.
If you will be driving it around you will want an A2A cooler. Just pulling or racing a W2A is better. Water injection alone works but unless you dont have room (you do) or an intercooler is outlawed, you will not find many people who would say not to run one in any diesel motorsport engine.
It wouldn't be hard to make, just get a big core or two smaller cores (maybe that flows vertically instead of horizontally. Either way basically you are wanting a tank on each side of the truck for each turbo to feed the hot side with at the bottom of the cooler. Then a tank at the top that can collect from both, or two tanks that run into a collector to feed the intake manifold.
If you go W2A, lots of guys just mount them right in the valley, then feed it from each side with your turbos, short pipes.
The issue is that its a Vee motor, finding room for a turbo on each side of the motor is not easy if that is what you want to do. Its easy and doable, theres just a ton of shit in the way. I can't see a significant performance reason to do it, but if you just want to be different I can understand that.
Another option is to mount them lower and forward of the motor. Look up forbidnns quad turbo truck.