Have fun stopping at 80-100mph with all the weight. Guess im getting old, dont want to kill anyone in my truck or someone else's.
Stopping at 80 isn't that bad with the brakes set right. And on a open road you don't need to stop. Driving fast is fine when in the right area. Drive to your area is key. Loaded in town I drive slower than the limit, to me I feel safe doing it.
I've always ran 75-80 pulling trailers and luckily never had tire trouble.
I just watch my tire pressure and in the summer set it at 5-10 psi under when cold. Works for me so I don't change it up. Lol. I use to pull 85-90 but quit that about 2 years ago, not worth the ticket anymore.
As care as tire age, most of my trailers see a 100 mile range and are on the tires they had when build. 07, 09, 12, 13, 13 and my other trailer gets tires ever year, it gets 50K miles being pulled across country at 8-10k.
All my trailers are 16" wheels, tires seem to work better for me, last longer. My friend has 15" wheels on his 5th wheel, I have 16" both are 3 axle, mine is heavier and he has a tire blow out yearly, he slowed down to 65 and still has a blow out yearly. I pull it 75-80.
Find what works for you and you feel safe with.