The S464 has a 73mm exducer , so 2 mm bigger than the S300 ,but the inducer is larger i believe , so yes it is going to be a touch laggier than the s300 , But it will support more HP also .
Dale just put a S464 on his LBZ , he has towed with it and said it worked real well . Don't get me wrong if cost didnt need to be considered i would choose the HTT , or S300 , but since a S4 series is almost a G cheaper and has a lot more room to upgrade later ( clear up to a 80mm on the same chassis / pedestal ) then it gets my vote for sure , plus one of these days i will have a twin kit to build off of the S464/466 !