Could it just be this tuner?
To your original question, YES.
If your fuel pressure was actually that low at WOT, I'm thinking you'd be popping codes and triggering limp mode. If it's not limping, I'm guessing it's feeding ya BS data. Some tuners or add on boxes used trickery to jack the pressure. I know the Quadzilla I tested on a Ford did, but have no experience with the Diablo on the Duramax.
First I'd put it back to stock and check it again at WOT. If it's a true fueling issue it will still be there. Ultimately you need to compare the requested fuel pressure to actual fuel pressure pids with a decent scanner. They should track within 1000lbs all the way up the scale.