we are not building a stock engine. by no means would i ever put a HX on bottom and H on top or vise versa for a single main or rod. For one, the bearings will not be matched and off .0005 at each lip of where they end. this dont seem like much but when clearances are down to the .0001, it very much is. running different upper and lower is a damn good way to put the crank out of center. rods have more leniency there but again, i wouldnt want to off set center of rod to the journal. the edges of the bearings will not create good wear patterns on the crank surfaces.
you can use a upper and lower HX on one main and a upper and lower H on another main as long as your clearances are within spec. IIRC, gm has 3 or 4 different bearing options. all a softer metal and all in much smaller incremental changes than .001. you will need to check my facts here but im recalling this from somewhere.
if clearances are off .001 or more after an align hone/bore, you have a bigger issue with your machine shop. if the block is not being align hone/bored, i can see a clearance issue being a problem IF you do not follow proper torque of the stock main bolts or deciding to add main studs.
if you guys are using plasti-gauge, you shouldnt be changing bearings around based on that.... this is a bore gauge and out side mic area that must be done with indicators readable down to .0001 to get the best results and a happy bottom end. just a few specs of dirt under the bearing can drastically change clearance.