I have run an S475 or larger single turbo on my daily driver truck since 2009. I have driven and tuned cast, billet, bat, double bat, and TCT wheels. On my truck I have run cast 75/83/.90, cast 75/83/1.0, cast 80/87/.90, Double Bat 75/83/1.0, TCT 75/87/1.0, and billet 80/87/.90. I tow when I need to (which has been at least once with each of those turbos), which is typically another Duramax on a trailer to and/or from an event. I have run cams that were not at all recommended for running a big single for spool up and streetability, yet still had great street manners. I have had numerous people ride with me and ask "what twins are on this" and be completely floored to find out it's an S480 single - "I've always heard big singles don't spool for $h*t, this can't be that big of a single with how fast it spools" or "You can't have that good of spool up and that much top end out of a single turbo".
You can very easily drive and tow with S475 and even larger turbos - but the whole setup of the truck needs to be right. The right converter, the right ECM and especially TCM tuning. Talk to LWatson or brandon06dmax, they both run S475s on stock CP3s in their DD trucks and LWatson tows with his fairly regularly.
I have also driven and tuned more S475 over stock trucks than I have cared to - in my opinion that is the worst compound setup ever - it spools worse than the stock turbo by itself and doesn't have anywhere near the top end power of the S475. The 475 compressor side chokes out the stock charger up until it (the 75) starts to spool and actually push air, then the stock charger is a huge choke point in the exhaust in the top end. Going to an S480 for the big charger will help the bottom end a good bit, but you are still very limited on the top end. I would save my money and time and drop a BatMoWheel in a stock turbo for better than stock spool and up to 635 rwhp for really cheap or if I wanted more than that and still better spool and more power than a stock/475 setup stick on a Danville 72mm billet VVT on by itself.
