I will put money on it that this is when the most damage is being done! It is when most are also failing and no load/light load from 1600-1800rpms is when I see the god-awful vibrations on the engine dyno with these motors. You can get it to "ring" when it does it! With the AF cams this vibration is drastically reduced. Stock cam makes the whole building shake and AF cam you only hear an audible sound. Combinations on parts alters it some but it is always in the same rpm window not matter what is tried.
Cruising rpm on my truck on the highway with the 35's is right in this rpm range. I know the sound you are talking about and am not surprised that this is where I was running when mine broke. Good to know the AF does help alleviate some of this.
Because of where mine broke, behind the number 4 main, I am confident in the harmonics being the biggest issue.
The ones that break behind number 1 main I believe are from extra loading of the gear train (from dual CP3's, 2nd alternator, higher spring tension for the valves possibly, higher load from modified oil pumps/reliefs, Mitusa pumps, etc), possibly bad dampners, and harmonics all combined. Or even individually plus harmonics alone.
Again, sucks to hear of a couple breakages with the AF cam, but I digress, without starting with new parts, it's tough to point the finger at one thing or the other. If the only parts changed after a breakage were the crank and cam, this would be the ideal scenario for a proper test. And the more done this way, the better the range of info is that can be gathered from future failures-or non failures even.
Need more of them out there with new cranks in DD's to get a better idea if it helps or not IMO.