Theres a good bit you can do with them, but to get alot out of them you need to look into the marine intake conversion for it. The stock central poppet injection set-up won't supply enough fuel to make alot of HP. A good cam and headewrs will wake one of the 5.7 VORTECS up a good bit, but you should look into the 1411 ECM swap for it(01 express PCM swap). The stock 256 MB PCM is OK, but very limited as far as tuning goes. The 383 swap is doable as well, but remember you can only run a single roller timing chain set-up in it due to the crank sensor and pick-up wheel. And the gear drive set-up will trigger teh knock sensors. The heads will need work to go above .450 lift, but you can do the conical valve springs and offset retainers and get up over .500 lift that way. If your just after a torque monster, then I would do the 383 swap, the COMP tri power mid level torque cam(degree'd in 3-4 degrees advanced), CLoyes single roller timing set, CRANE cam spring and retainer set, a mild port match on the heads and intake, modify the throttle body to remove the air foil, and a set of mid length or long tube headers. If you go much more the injectors simply won't keep up and you wil lhave to do the marine intake swap and custom tuning.