The .75 4th gear of the 85E is very close to the .71 5th gear of my 5 speed Allison in my 1/2 ton LLY. I have 3.42 gears with the same 275/55R20 tires in my truck. 3.42 are decent, and I have actually thought about going to a 3.23 gear to bring down my cruising RPM (around 2000 between 70 and 75). How much does your vehicle weigh? I think you'd be happy with either a 3.42 or a 3.23. If you want it a little better acceleration with that 2.48 1st gear, I'd say do the 3.42. If you want a little lower cruising RPM, I'd say do the 3.23. If I could find a set of 3.23s for the 8.5 IFS front diff in my truck I'd swap, that's the only thing that keeps me from doing it. Although my 3.10 first gear helps me get out of the hole better than your 2.48 will.
What are you doing for a converter? That will be a factor too, you could run a looser converter and still get away with the 3.23s.
I had 3.73 in my truck originally and it was too much.
FWIW, here are the ratios between the 5 speed Allison and the 4L85E:
Gear----Allison----4L85E
1--------3.10------2.48
2--------1.81------1.48
3--------1.41------1.00
4--------1.00------0.75
5--------0.71