Pinion angle depends on MANY factors. Will it still have single cardan's at each end, or will you be going with a double cardan CV type at the transfer case. If you run a single cardan at each end, then each u joint needs to have roughly the same angle as the other within +/- 3 degrees max to keep the driveline semi smooth, but +/-1 degree is optimal. Angled blocks are if you drop the transfer case down to try and maintain lesser angle on your u-joints. If you drop the transfer case you lessen the angle at the transfer case to shaft connection, so you need to go an equal amount at the diff to driveshaft connection. If you don't drop the transfer case, then in most cases you do NOT want to run an angled block. Now if you go with a double cardan CV type joint at the transfer case side, then you want to run the driveshaft at the diff side down 1-3 degrees from level so that under hard torque, the driveshaft will go straight. HARD launching drag cars will often times run 3-6 degrees of down angle because under hard launches, it will torque that far even with all solid connections(ran 4 degrees down on our car, but it weighed around 1950lbs and did 1.06 60 footers tripping the beams with the rear tires).
Heres a basic breakdown of a single cardan type shaft.
http://www.youtube.com/watch?v=gmV4qwLfOMY